Permethylation of glycans converts hydrogen groups to methyl groups which renders the glycans hydrophobic; the conversion stabilises sialic acids and can increase signal intensity in mass measurements.

permethylated igg image

A mixture of fucosylated, bi-antennary glycan standards with variable sialylation
released from human IgG antibody glycoprotein and permethylated.

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20 MS runs

Part Number: CPM-IGG-01