Capture and Cleanup

QA-Bio offers a number of products for glycan capture and cleanup after enzyme digestions and molecular labeling. Cartridges and plates bind glycans but allow contaminants to be washed through.

Glycan Purification – Remove Proteins, Salts, and Detergents
Exoglycosidase Clean-up Plate – a high-throughput option for the removal of enzymes after enzymatic digestion.
Exoglycosidase Clean-up Cartridges – for removal of enzymes post-exoglycosidase digestion of glycans.
A Cartridges have been developed for glycopeptide enrichment from a peptide/glycopeptide mixture after protease digestion.
EC50 96-Well Plate – a high throughput option for the purification of glycans from complex mixtures including proteins, salts, and detergents.
EC50 Cartridges – developed as a lower cost replacement for the EB10 cartridges while having equivalent efficiencies and reproducibility.
EB10 Cartridges – contain a unique graphitised carbon material, a super-hydrophobic resin that binds even very hydrophilic glycans
CEX Cartridges – purification of O-glycans from salts, proteins, and detergents.

Glycan Cleanup After Labeling Reactions
Procainamide Clean-up Plates – removes excess procainamide label after labeling of glycans.
S Cartridges – one of the most reliable methods for achieving post-labeling cleanup
T1 Cartridges – faster purification of glycans after labeling with the 2-AB and 2-AA

Velocity Manifold System
The Velocity System is a 96 well microplate vacuum manifold system which enables analysts to process up to 96 samples simultaneously. The system can be used with individual clean up cartridges or 96 well plate cleanup devices.

LC-EXO-96 Exoglycosidase Clean-up Plate
US$265

The Ludger Exoglycosidase Clean-up Plates are a high-throughput option optimized for the removal of enzymes after exoglycosidase digestion or sequencing of glycans. Use of these 96-well plates prevents the contamination of HPLC columns during subsequent chromatographic analysis.

View product documentation:
Product Specsheet/SDS
Certificate of Analysis Search

Contains one 96-well plate

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Part Number: LC-EXO-96

US$940

The LudgerClean EC50 cartridges have been developed as a lower cost replacement for the EB10 cartridges while having equivalent efficiencies and reproducibility. Purify glycans from complex mixtures including proteins, salts, and detergents.

Applications include cleanup of glycans following hydrazinolysis, endoglycosidase digests (including PNGase F digests), enzyme treatment, and before and after fluorescent labeling.

View EC50 online presentation

View product documentation:
Product Specsheet/SDS
Certificate of Analysis Search

contains 24 cartridges

Part Number: LC-EC50-24

US$289

Ludger EB10 cartidges have been designed for purification of glycans from proteins, salts, and detergents.

Applications include cleanup of glycans following hydrazinolysis, endoglycosidase digests (including PNGase F digests), enzyme treatment, and before and after fluorescent labeling.

View product documentation:
Product Specsheet/SDS
Certificate of Analysis Search

contains 6 cartridges

Part Number: LC-EB10-A6

US$202

The Velocity Collection Plate is a component of the the Ludger-Velocity Vacuum System developed for glycan clean-up during high-throughput analysis

Pack of five Velocity Collection Plates – 96 well

View product documentation as PDF

Part Number: LP-COLLPLATE-2ML-96

US$141

The Velocity Cartridge Holder is a component of the the Ludger-Velocity Vacuum System developed for glycan clean-up during high-throughput analysis.

A 96 well plate developed to house cleanup cartridges when using the Velocity Vacuum System

View product documentation as PDF

Part Number: LP-HOLDER-96

US$69

The Velocity Plug Pack is used to seal empty wells prior to the application of vacuum when using the Velocity Vacuum System for high-throughput glycan analysis.

12 strips of 8 plugs

View product documentation as PDF

Part Number: LP-PLUG-96

US$162

One of the most reliable methods for achieving post-labeling cleanup is use of S-cartridges.

They are routinely used in the biopharma industry during glycoprofiling QC for lot release of FDA and EMA approved biopharmaceuticals.

View product documentation:
Product Specsheet/SDS
Certificate of Analysis Search

contains 6 cartridges

Part Number: LC-S-A6